Factors Associated With In Vitro Interferon-gamma Production in Tuberculosis
نویسندگان
چکیده
منابع مشابه
Interferon-Gamma Gene Polymorphism in Patients with Tuberculosis
Abstract Background and objectives: Interferon-Gamma and interferon Gamma receptor (IFNγ ⁄ IFNγR1) are the main genes associated with susceptibility to tuberculosis. We aimed at studying on interferon-Gamma Gene polymorphism(- 56 C/T) in people suffered from tuberculosis (TB). Material and Methods: In this case-control study, the subjects were 62 individuals with TB and 74 hea...
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Background: Interferon gamma (IFN-γ), a cytokine produced by a variety of cells is involved in the immune response against M. tuberculosis. It activates the production of other cytokines and molecules that kill mycobacterium. IFN-γ also has diagnostic role in identification of active and latent tuberculosis. Objective: To determine the level of IFN-γ in the blood of TB patients. Methods: Ninety...
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The tuberculin skin test (TST) is the "gold standard" for detecting infection with Mycobacterium tuberculosis. We compared the TST using purified protein derivative to the QuantiFERON-TB test (QFT). Two groups were examined. Group 1 individuals (n = 66) (low risk) were at low risk for exposure to M. tuberculosis and were not Mycobacterium bovis BCG vaccinated. Group 2 (n = 29) include individua...
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It is not clear why some individuals with unknown predisposition develop tuberculosis, while others remain healthy in spite of heavy exposure. Interferon gamma (IFNgamma) is considered to be the key cytokine responsible for resistance to M. tuberculosis infection, as confirmed by increased susceptibility to mycobacterial infections in rare inherited defects in IL-12-IFNgamma axis. The aim of th...
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Background and purpose: Delay in diagnosis and treatment of tuberculosis (TB) patients with positive sputum is a main reason for spread of the disease. The present study aimed at investigating delayed diagnosis and treatment of patients with positive tuberculosis in Sistan, Iran. Materials and methods: This cross sectional study was conducted among 384 patients with positive smear tuberculosis...
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ژورنال
عنوان ژورنال: Journal of the Formosan Medical Association
سال: 2011
ISSN: 0929-6646
DOI: 10.1016/s0929-6646(11)60036-3